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Can You Take Too Much Magnesium?

Can You Take Too Much Magnesium?

In the modern era, there is a tendency towards taking things to the extreme, especially regarding health and wellness practices.

New theories, methodologies, and lifestyle ideas often trigger a knee-jerk reaction, causing us to dive headfirst into adopting these mantras without thoroughly vetting them or understanding their implications.

Take, for instance, your newfound knowledge of the health benefits of vitamin D.Enthused; you begin consuming 10,000 dietary supplements containing Vitamin D a day without even blinking, not realizing that excessive intake of this vitamin can lead to toxicity.

It is important to note that consuming nutrients within the recommended dietary allowance, known as adequate intake, is crucial for maintaining optimal health.

Then there's the talk about the requisite water intake we must meet daily. You hear "10 cups" and diligently start consuming this quantity, oblivious to the potential harm it could cause. Excessive water consumption could inadvertently lead to a condition called hyponatremia, where electrolyte levels become dangerously low due to water dilution.

Or consider the humble liver, often touted as one of the healthiest foods to incorporate into our diet. Spurred on by these claims, you begin consuming a beef liver every day, unaware that such a move could increase your susceptibility to vitamin A and copper toxicity.

Friends, jumping on the bandwagon without a sound understanding is not the path to health.

Case in point: The case of the ‘magnesium hype.’ Indeed, magnesium, like all minerals, plays an indispensable role in our body. However, it's vital to tailor the intake to our needs rather than sticking to a generic dosage or blindly following someone else's regime without consulting medical advice or lab results.

It is worth noting that there is some evidence suggesting that the use of magnesium supplements, such as magnesium sulfate, might help prevent or reduce symptoms of migraine headaches. However, it is essential to remember that not all research agrees on this.

Therefore, it is crucial to consult with a healthcare professional before considering high doses of magnesium citrate for migraine prevention.

It is also essential to be aware that taking high doses of magnesium citrate may lead to side effects such as muscle weakness and diarrhea, especially in some individuals and those with certain medical conditions.

The National Headache Foundation suggests a daily dose of 400-600 mg of magnesium to reduce the frequency of migraine attacks. However, it is essential to note that exceeding the recommended daily allowance (RDA) may result in side effects and be unsafe for everyone, especially those with certain medical conditions.

Therefore, discussing high-dosage magnesium supplements with a physician is advisable.

In this context, we will guide the conversation today towards understanding what could happen if we overdose on magnesium, explicitly discussing the likelihood of such a scenario and how you can discern whether you require this mineral supplement or not in the first place.

The Importance of Magnesium

To begin with, let's delve into the significance of magnesium and its primary functions.

Magnesium, an essential mineral, is a critical component that contributes to several physiological processes in the human body. Besides being a crucial factor in maintaining good health, magnesium also serves as a cornerstone for a vast array of bodily functions.

Here are some key reasons why magnesium is essential:

Muscle Function

Magnesium plays a pivotal role in the proper functioning of our muscles, overseeing both their contraction and relaxation. It collaborates with calcium to regulate muscle contractions, and maintaining adequate magnesium levels can help fend off muscle cramps and spasms.

Energy Production

As a cofactor for various enzymes, magnesium is instrumental in producing energy within our body. It plays a particularly significant role in synthesizing ATP (adenosine triphosphate), the primary energy source for cells.

Nervous System Function

Magnesium is critical in regulating neurotransmitters, the chemical messengers responsible for transmitting nerve signals. By maintaining a healthy nervous system, magnesium reduces stress and overall mental wellness.

Bone Health

As a crucial component of bone structure, magnesium is indispensable for the appropriate metabolism of calcium and vitamin D - both critical factors in building healthy bones and teeth. Consequently, adequate magnesium levels contribute to a more robust skeletal framework.

Heart Health

For optimal heart health and proper blood vessel function, magnesium is essential. Not only does it help maintain a regular heartbeat, but it also works to regulate blood pressure. As a result, adequate magnesium intake has been linked to a decreased risk of cardiovascular diseases.

Blood Sugar Regulation

Magnesium is implicated in insulin sensitivity and glucose metabolism, two factors that significantly influence the regulation of blood sugar levels. By maintaining healthy blood sugar levels, magnesium becomes an essential ally in preventing and managing diabetes.

DNA and RNA Synthesis

As a key participant in synthesizing nucleic acids (DNA and RNA), magnesium helps create the genetic material within our cells. Its involvement is essential for proper cell division, growth, and overall cellular integrity.

Protein Synthesis

Magnesium's role in the body extends to the production of proteins, as it functions as a cofactor for various enzymes involved in this process. The synthesis and maintenance of proteins are crucial to the body's function and overall well-being.

Electrolyte Balance

Working in harmony with other minerals such as sodium, potassium, and calcium, magnesium maintains the body's electrolyte balance. This balance is vital for optimal bodily function and overall health.

Mood and Sleep Regulation

Studies have linked magnesium intake to improved mood and enhanced sleep quality. Furthermore, this essential mineral regulates neurotransmitters that directly influence mood and sleep patterns, contributing to a better quality of life.

The Likelihood of Magnesium Deficiency

The likelihood of magnesium deficiency isn’t as understood as we’d like it to be, but an estimated 2% of the general population apparently has a magnesium deficiency, but this percentage sky rockets to close to 50% of individuals who are hospitalized, and 70-80% of individuals who are in their 70s or older.

This estimation is most likely an under estimate because many of these calculations are typically done via serum, and that is a poor measurement of magnesium to begin with.

Magnesium is an intra cellular mineral, meaning it is found in the cell- not the blood, and the little amount we do have circulating in our blood is there as a regulator.

The body maintains this level, even in times of illness, hence deficiency isn’t always as easily detected unless the body is in critical condition.

The best way to actually measure any intra cellular mineral is through a tissue biopsy- but I don’t see anyone doing that sort of crazy thing.

So, the next best thing is by running a Hair Tissue Mineral Analysis (HTMA) through us, where we measure the level of excretion and interaction amongst other elements to get a picture of one’s magnesium status.

Signs of Magnesium Deficiency

What are the signs and manifestations of magnesium deficiency?

A magnesium deficiency, referred to medically as hypomagnesemia, can result in an array of symptoms impacting numerous bodily systems. Remember that the presentation of these symptoms can be quite subtle, often varying from person to person.

Muscular Disturbances

Magnesium plays a critical role in muscle functionality. When your body lacks this vital mineral, it may manifest symptoms such as muscle weakness, uncontrollable spasms, painful cramps, and prevalent fatigue.

These indicators are particularly prominent in physically active individuals who require effective muscle contraction and relaxation.

Chronic Fatigue and Weakness

Magnesium is fundamentally involved in generating ATP, the primary energy source for the body's cellular functions. Consequently, a magnesium deficiency can result in persistent tiredness and weakness, lowering overall productivity and affecting general well-being.

Gastrointestinal Discomfort

One of the less-anticipated yet common signs of magnesium deficiency involves the digestive system. Low levels of magnesium may trigger uncomfortable gastrointestinal symptoms, including nausea and vomiting.

These symptoms can vary in intensity and frequency.

Diminished Appetite

As part of its wide-reaching effects on the body, a magnesium deficiency can significantly reduce appetite or even food aversion.

This change may not be connectable to dietary changes or preferences, marking it as a possible sign of magnesium deficiency.

Cardiac Irregularities

Magnesium plays an essential part in sustaining the heart's regular rhythm. With decreased magnesium levels, you may experience irregular heartbeats (known medically as arrhythmias) or palpitations.

These symptoms can range from harmless changes to critical disruptions in heart functionality, underlying its importance in heart health.

Numbness or Tingling Sensations

Individuals suffering from magnesium deficiency may start experiencing numbness or a "pins and needles" sensation, typically pronounced in the extremities (hands and feet).

These sensations may initially be intermittent before gradually becoming more persistent and causing significant discomfort.

Alterations in Personality

Magnesium significantly regulates neurotransmitters, the molecular gatekeepers impacting mood and behavior. As such, a deficiency might lead to noticeable changes in an individual's mental state, such as increased anxiety levels, mood swings, incidences of depression, or variations in general temperament.

Risk of Seizures

In severe cases of magnesium deficiency, the likelihood of experiencing seizures can go up considerably. This can also be exacerbated if the individual has a historical predisposition to seizures or epilepsy.

Unusual Eye Movements

Magnesium plays a vital role in neuromuscular functionality, including eye movement control. Consequently, a deficiency can manifest as erratic eye movements that are out of sync with standard control, enough to be noticeable to an observer.

Reduced Calcium Levels

Magnesium and calcium share a close relationship within the body's physiological mechanisms, with the former helping regulate the latter's levels. Therefore, a magnesium deficiency can result in abnormally low calcium levels, which might further trigger symptoms like unexplained muscle spasms or twitching.

Consideration for Other Nutrient Deficiencies

While it's true that magnesium deficiencies are commonplace, it's crucial to recognize that nutrient imbalances or deficiencies can elicit similar symptoms in the body.

Take numbness or tingling, for example. It can certainly be a symptom of magnesium deficiency, but it might also indicate deficiencies in other nutrients such as Vitamin B12, B6, or even potassium.

Personality changes, another potential indication of low magnesium levels, can also result from decreased sodium levels. Seizures, too, can be triggered by multiple factors, not just a lack of magnesium.

Moreover, a loss of appetite, which might hint at a magnesium deficiency, is often primarily associated with zinc deficiencies.

Given the overlapping nature of these symptoms among various nutrient deficiencies, it's far too nuanced a field for an individual to navigate based on a single element or symptom. Therefore, we strongly advocate for comprehensive testing rather than resorting to supplementation based solely on guesswork.

Knowing the precise nutritional state of your body helps you make informed and targeted improvements to your dietary regimen.

The control groups in randomized clinical trials have shown similar effects as the treatment group receiving elemental magnesium supplements, indicating that magnesium supplementation may not be an effective treatment for depression.

The Repercussions of Magnesium Overdose

So, what can happen if you consume excessive amounts of magnesium over an extended period?

First and foremost, it's essential to understand that an overabundance of magnesium can lead to the depletion of other essential minerals, such as calcium, sodium, and potassium. These minerals are vital in maintaining your body's health and overall well-being.

A decrease in calcium levels can manifest as a poorly regulated nervous system, accompanied by challenges like poor sleep, anxiety, and unstable blood sugar levels, and without enough magnesium, these areas malfunction.

Meanwhile, diminishing sodium levels can be associated with issues related to adrenal function, depression, and dehydration. Additionally, chronic fatigue syndrome (CFS) can also be linked to inadequate levels of magnesium.

Impaired cognitive abilities and chronic fatigue are symptoms that can be improved by administering magnesium as a shot, according to some research.

However, the effectiveness of magnesium in treating CFS is still a topic of debate among researchers. It is worth noting that magnesium supplementation has shown potential in relieving skeletal muscle cramps, as suggested by studies (Razzaque MS, Garrison SR, et al., 2018; Garrison SR et al., 2012).

Low potassium in the body can result in an underactive thyroid, unstable blood sugar levels, repeated episodes of fatigue, and dehydration.

In more extreme instances, an excess of magnesium, which typically occurs from over-supplementing, can lead to a range of severe symptoms, including nausea, vomiting, weakness, facial flushing, low blood pressure (diastolic blood pressure), irregular heartbeat, cardiac arrest, and confusion.

People with kidney disease have a higher risk of toxicity because their kidneys are not working correctly and cannot flush out extra magnesium. In the most severe cases, an overabundance of magnesium, such as from the use of proton pump inhibitors, can culminate in a coma.

Additionally, a grouping of symptoms that increase the risk of diabetes, heart disease, and stroke (metabolic syndrome) has been linked to low magnesium levels.

People with normal magnesium levels are 6-7 times less likely to have metabolic syndrome than those with low magnesium levels.

Higher magnesium intake from diet and supplements is associated with a lower risk of developing metabolic syndrome in healthy adults.

Magnesium deficits and increased urinary magnesium excretion can occur in people with insulin resistance and type 2 diabetes, highlighting the importance of maintaining adequate magnesium levels.

In 2022, the FDA approved a qualified health claim for conventional foods and dietary supplements that contain magnesium. Dieting with adequate magnesium may reduce the risk of high blood pressure (hypertension). 

To maintain a balanced magnesium intake and other essential minerals, monitor your dietary habits carefully and only consider supplementation when advised by a healthcare professional.

The Case for Safe Supplementing

The intention here is not to deter you from considering supplementation but to ensure you approach it cautiously and with sound knowledge. The reality is that most people could benefit from supplementation due to the relative scarcity of magnesium in our everyday foods.

This deficiency largely stems from several interconnected factors. Poor farming practices, excessive use of heavy metals and fertilizers, absence of crop rotation, and the hybridization of food - all these factors have progressively eroded the nutritional value of crops, including the level of crucial minerals such as magnesium.

Given these circumstances, it's understandable why supplementation could be beneficial for maintaining optimal nutritional status and addressing various health conditions. However, practicing safe and balanced dosing is critical, considering the intricate relations between different minerals in the body.

Each one exerts a domino-like influence on the others, so it's essential to strike a harmonious balance for holistic mineral health. Just like the body's spark plugs, minerals play a significant role in metabolism and the energy that runs the entire body.

They help build and activate enzymes, which are proteins that speed up chemical reactions in the body. All of our cells need enzymes to work correctly.


In conclusion, maintaining an optimal balance of magnesium is pivotal to our overall health, given its myriad biological functions, from muscle contractions, energy production, and bone health to sleep regulation.

While we recognize the potential benefits of magnesium supplementation due to its scarcity in contemporary food sources, we caution against the impulse to overload on it.

Over supplementation, based on hearsay or misconstrued information, can lead to an array of adverse health implications, making the adage "too much of a good thing" hold. Therefore, it is crucial to consider your health status and nutritional needs as guided by professional consultations and tests like HTMA.

The goal is to strike a harmonious balance in our mineral intake, not just for the sake of magnesium but to ensure optimal mineral health.

Let's shift from guessing to tested, personalized plans – because your health deserves nothing less.

Schedule your HTMA with us today!


Barbara Madimenos
Hair Tissue Mineral Analysis Practitioner
Functional Diagnostic Nutrition Practitioner
Integrative Nutrition Coach

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